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党参多糖的提取、结构表征、生物活性及食品应用

Extraction, structural characterization, biological activity and food applications of polysaccharides from Codonopsis pilosula.

科研进展PubMed 论文机译
  • 期刊Carbohydrate research(Carbohydr Res)
  • 发表时间2026-10-03
  • 作者Zhang H, Du R, Xiao J, Xu X, Yang C, Kuang H, Wang Z
  • 卷期页码V570 : 110120
  • 文献类型Review
  • DOI10.1016/j.carres.2026.110120
  • PMID42837913

摘要机译

党参在中国作为药用草药已有数千年的历史,具有显著的营养和药用价值。2023年,党参被正式列入国家药食同源名录,显示了其在食品工业中的巨大潜力。党参多糖(CPPs)是党参的主要生物活性成分之一。

本综述总结了近五年来在提取和纯化CPPs方面取得的最新进展,对传统方法和新方法进行了批判性评价。

对CPPs的结构特征进行了深入研究,阐明了单糖组成、糖苷键、分子量和高级构象特征之间的关系。此外,还综述了CPPs的生物活性和药代动力学,以及它们在食品工业中的潜在应用。这一综述为药物开发和食品工业应用奠定了基础。

展开英文摘要原文

Codonopsis pilosula (Franch.) Nannf. has been used as a medicinal herb in China for thousands of years and possesses significant nutritional and medicinal value. C. pilosula was officially included in the national list of medicine-food homology in 2023, indicating its great potential in the food industry. Codonopsis pilosula polysaccharides (CPPs) are one of the primary bioactive components of C. pilosula and have garnered increasing interest due to their wide range of biological activities. This review summarizes the latest advancements in the extraction and purification of CPPs over the past five years, providing a critical evaluation of both traditional and new methods. It also conducts in-depth research on the structural characterization of CPPs, clarifying the relationship among monosaccharide composition, glycosidic bonds, molecular weight and advanced conformational characteristics. Furthermore, the biological activities and pharmacokinetics of CPPs are reviewed, along with their potential applications in the food industry. This review lays the groundwork for drug development and food industry applications.

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