- 期刊Natural product research（Nat Prod Res）
- 发表时间2026-11-06
- 作者Vadariya HA, Mehta NA, Haldar S, Adimurthy S
- 卷期页码1-5
- DOI10.1080/14786419.2026.2755886
- PMID42989994
摘要机译
姜黄是一种被广泛认可的药用植物，其生物活性成分，特别是姜黄类化合物和阿魏酸，具有很强的抗氧化、抗炎和治疗特性。本研究开发了一种选择性水基提取方法，用于同时从姜黄粉末中回收姜黄类化合物、阿魏酸和淀粉。
最佳提取条件（10%w/v NaOH，80°C，4 h）实现了有效的分馏，甲醇有效地保存了姜黄素类化合物。分离化合物的同一性和纯度通过光谱分析得到证实。定量分析显示姜黄样品中姜黄素的回收率为0.50%-4.10%，阿魏酸的回收率为1.40%-1.95%。
抗菌试验显示姜黄素和阿魏酸对蜡样芽孢杆菌、大肠杆菌、铜绿假单胞菌和阿莱泰葡萄球菌均有剂量依赖性活性。阿魏酸对阿莱泰葡萄球菌和蜡样芽孢杆菌有很强的抑制作用，但对大肠杆菌和铜绿假单胞菌的抑制作用较弱，而姜黄素显示中等活性。
展开英文摘要原文
Turmeric (Curcuma longa L.) is a widely recognised as medicinal plant valued for its bioactive components, particularly curcuminoids and ferulic acid, which exhibit strong antioxidant, anti-inflammatory, and therapeutic properties. In this study, a selective aqueous-based extraction method was developed for the simultaneous recovery of curcuminoids, ferulic acid, and starch from turmeric powder. Optimal extraction conditions (10% w/v NaOH, 80 °C, 4 h) enabled efficient fractionation, with methanol effectively preserving curcuminoids. The identity and purity of the isolated compounds were confirmed by spectroscopic analysis. Quantitative analysis showed curcumin recovery of 0.50%-4.10% and ferulic acid recovery of 1.40%-1.95% from turmeric samples. Antibacterial testing revealed dose-dependent activity for both curcumin and ferulic acid against Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus arlettae. Ferulic acid displayed strong inhibition against S. arlettae and B. cereus, but weaker effects against E. coli and P. aeruginosa, while curcumin showed moderate activity.
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